Lab Members‎ > ‎

Mukesh Mahajan

mukeshm@umich.edu

Biophysics
930 N. University Ave.
Ann Arbor, MI 48109

(734) 763-9318

Academic Background

Ph.D. Structural Biology and Biochemistry, Nanyang Technological University, 2014, Singapore

M.Tech. Bio-Technology, (
Cum Laude) HNB Garhwal University (A Central University), 2008, India

B. Pharmacy. Pharmaceutical Sciences, Punjab Technical University, 2005, India

D. Pharmacy. Punjab State of Technical Eductaion and Industrial Training, 2001, India

Research project

Structure based functional dynamics of Cytochrome P450 and its redox partners in Lipid membranes

Professional experiences

Teaching Assistant: CASE Western Reserve University, 2015-2016, Ohio, USA

Teaching Assistant: Nanyang Technological University, 2009-2013, Singapore

Lecturer: Beant College of Engineering and Technology (A State Govt. Engineering College), 2008, India

Occupational Health Pharmacist: Jagatjit Cotton Textiles Mills, Hoshiarpur, 2005, India

Hospital Pharmacist: Govt. Civil Hospital, Hoshiarpur (2001-2003), India

Publications

Prade E., Mahajan M., Im S.C., Zhang M., Gentry K., Anantharamaiah G. M., Waskell L. and Ramamoorthy A. A Minimal Functional complex CYP450 and FBD of Cytochrome P450 reductase in Nanodiscs. (Manuscript accepted in Angewandte chemie).

Ravula T., Barnaba C., Mahajan M., Anantharamiah G.M., Im S.C., Waskell L., Ramamoorthy A. The Membrane Environment Drives Cytochrome P450’s Spin Transition and its Interaction with Cytochrome b5. Chem. Commun. 2017, 53, 12798-12801.

Gentry K., Prade E., Barnaba C., Zhang M., Mahajan M., Im S.C., Anantharamaiah G. M., Nagao S., Waskell L. and Ramamoorthy A. Kinetic and Structural Characterization of the Effects of Membrane on the Complex of Cytochrome b5 and Cytochrome c.Scientific Reports, 2017, 7: 7793.

Conferences

Mahajan M., Prade E., Gentry K., Im S.C., Waskell L. and Ramamoorthy A. High Resolution Functional Interaction of A Minimal CYP450-Redox Complex in Lipid Bilayer. Poster presentation at The Protein Society, Boston, USA, May 2018.

Sumangala N., Mahajan M., Ravula T. and Ramamoorthy A. Cytochrome-P450’s Spin State Influences its Binding Afinity to its Redox  Partners. Poster presentation at Biophysical Society, USA 2018

Mahajan M., Prade E., Zhang M., Gentry K., Im S.C., Anantharamaiah G. M., Waskell L. and Ramamoorthy A. High Resolution Probing of the Role of the Membrane on the CPR-CYP2B4 interacting interface and and electron transfer pathways. Poster presentation at Great Lakes Drug Metabolism and Drug Disposition Symposium at Western Michigan University, Kalamazoo, Michigan, USA, May 2017.

Gentry K., Prade E., Barnaba C., Zhang M., Mahajan M., Im S.C., Waskell L. and Ramamoorthy A.  Membrane influences the structure, dynamics, and kinetics of cytochrome-b5-cytochrome-c complex. Poster presentation at Great Lakes Drug Metabolism and Drug Disposition Symposium at Western Michigan University, Kalamazoo, Michigan, USA, May 2017.
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