Lab Members‎ > ‎

Kamal Mroue

mrouek@umich.edu


Biophysics
The University of Michigan
930 North University Avenue
Ann Arbor, MI 48109 – 1055

Phone: (734) 763–9318

Education

Ph.D. in Chemistry, 2010
  University of Waterloo, Waterloo, Ontario, Canada
Advisor: William P. Power
Thesis: "Solid-State NMR Investigations of 67Zn and 27Al Nuclei in Zinc-Amino Acid Complexes, Zinc-Insulin Hexamers, and Aluminum-Centered Dyes"

Research Projects

  • Development of novel solid-state NMR techniques and their applications to characterize membrane proteins, bone materials,  and nanomaterials like dendrimers.
  • Quantum chemical calculations of anisotropic NMR interaction tensors to extract structural information on exciting biomolecular systems.

Publications

  • K. Higashi, K. Yamamoto, M.K. Pandey, K.H. Mroue, K. Moribe, K. Yamamoto and A. Ramamoorthy. "Insights into Atomic-Level Interaction between Mefenamic Acid and Eudragit EPO in a Supersaturated Solution by High-Resolution Magic-Angle Spinning NMR Spectroscopy." Molecular Pharmaceutics (2013). DOI: 10.1021/mp4005723.
  • J.P. McElderry, P. Zhu, K.H. Mroue, J. Xu, B. Pavand, M. Fang, G. Zhao, E. McNerny, D.H. Kohn, R.T. Franceschi, M.M. Banaszak Holl, M.M.J. Tecklenburg, A. Ramamoorthy, and M.D. Morris. "Crystallinity and compositional changes in carbonated apatites: Evidence from 31P solid-state NMR, Raman, and AFM analysis." Journal of Solid State Chemistry (2013), 206, 192–198.
  • A.K. Chattah, K.H. Mroue, L.Y. Pfund, A. Ramamoorthy, M.R. Longhi, and C. Garnero. "Insights into Novel Supramolecular Complexes of Two Solid Forms of Norfloxacin and β-cyclodextrin." Journal of Pharmaceutical Sciences (2013), 102, 3717–3724.
  • K.H. Mroue, N. MacKinnon, J. Xu, P. Zhu, E. McNerny, D.H. Kohn, M.D. Morris, and A. Ramamoorthy. "High-Resolution Structural Insights into Bone: A Solid-State NMR Relaxation Study Utilizing Paramagnetic Doping." The Journal of Physical Chemistry B (2012), 116, 11656−11661.
  • K.H. Mroué and W.P. Power. "High-Field Solid-State 67Zn NMR Spectroscopy of Several Zinc – Amino Acid Complexes." The Journal of Physical Chemistry A (2010), 114, 324−335.
  • K.H. Mroué, A.M. Emwas, and W.P. Power. "Solid-state 27Al nuclear magnetic resonance investigation of three aluminum-centered dyes." Canadian Journal of Chemistry (2010), 88, 111−123.
  • K.H. Mroue, S.B. Andrey, M.L. Chan, J. Gu and W.P. Power. "Insights into the Zinc-Binding Sites in Insulin Hexamers by High-Field Solid-State 67Zn NMR Spectroscopy." (2010) In Progress.