Paul Smith (Chinese name: Fucheng Guo)
Biophysics Program 930 N. University Ave. Ann Arbor, MI, 48109 (734) 763-9318
Education
August 2016-present Exchange visitor, Biophysics, University of Michigan, Ann Arbor, Professor A. Ramamoorthy
September 2014-present Undergraduate student, Po Ling Class, College of Chemistry, NanKai Univeisity, Tianjin, China.
August 2013-September 2014 Undergraduate student, College of Pharmacy, NanKai Univeisity, Tianjin, China.
Research Projects
I am studying how to use some molecular inhibitors to affect the aggregation of Aβ40 in vitro. People think that Alzheimer's disease(AD), which manifests in progressive neurodegeneration, is characterized by the presence of amyloid-β(Aβ) peptide aggregates. However, the mechanism for the formation of Aβ aggregates is not entirely understood. We try to affect the aggregation of Aβ by means of inhibitors and then explore a kind of therapeutics for AD