*Welcome to Nazifa Tasnim Ahmad, Graduate Student, Biomedical Engineering!

*Welcome to Falak Syad, Graduate Student, Biomedical Engineering!

*Welcome to Dr. Naiem Wani, Post-Doctoral Fellow!

*Welcome to Dr. Pradeepraj Durairaj, Post-Doctoral Fellow!

*Welcome to Nabila Bushra, a Physics Graduate Student from the University of South Florida, Tampa, to the Rams Lab!

*Welcome to Debasmita Banerjee, Biophysics Graduate Student, FSU to the Rams Lab!

*Welcome to Sarayu Vanga, High School Student, to the Rams Lab!

*Welcome to Dr. Jhinuk Saha, a post-doctoral fellow, to the new lab!  

*Welcome to Dr. Malitha C Dickwella Widanage, a post-doctoral fellow, to the new lab! 

*Samuel McCalpin (jointly with Dr. Ivanova), Volodymyr Hiiuk (jointly with Prof. Nagorny), Gaurav Sharma (jointly with Dr. Ivanova), and Zhizhuo Zhang (jointly with Dr. Ivanova) are continuing at Michigan.  

Prof. Rams Ramamoorthy joins NHMFL+FSU on Aug. 01, 2023. 

• Website in progress: https://nationalmaglab.org/staff/?name=AyyalusamyRamamoorthy

• https://insi.fsu.edu/faculty

• https://www.youtube.com/watch?v=CX7ZeXjROfc

Transitioning:     Professor Ramamoorthy will be joining NHMFL (https://nationalmaglab.org/) and the Chemical & Biomedical Engineering Department at FAMU-FSU in Tallahassee on August 01, 2023. 

https://eng.famu.fsu.edu/cbe

Congratulations, Krishna, Gaurav and Thiru!

"Characterization of nanodisc-forming peptides for membrane protein studies", Krishnarjuna B, Sharma G, Im SC, Auchus R, Anantharamaiah GM, Ramamoorthy A. J Colloid Interface Sci. 2023 Sep 29;653(Pt B):1402-1414.

Congratulations, Sam, Malitha and Riqiang!

• "On-Pathway Oligomer of Human Islet Amyloid Polypeptide Induced and Stabilized by Mechanical Rotation During MAS NMR", McCalpin, Samuel; Widanage, Malitha ; Fu, Riqiang; Ramamoorthy, Ayyalusamy. J. Phys. Chem. Letters (in press). 

Congratulations, Bikash!

• Direct interaction between the transmembrane helices stabilize cytochrome P450 2B4 and cytochrome b5 redox complex, Bikash R. Sahoo, Ayyalusamy Ramamoorthy, Biophys. Chem. (in press).

Congratulations, Manjeet!

• Non-micellar ganglioside GM1 induces an instantaneous conformational change in Aβ42 leading to the modulation of the peptide amyloid-fibril pathway, Manjeet Kumar, Magdalena Ivanova, Ayyalusamy Ramamoorthy, Biophys. Chem. (in press).

• 
  

Krishna has accepted an offer from Michigan State University to join the Tuo Wang lab. Congratulations, Krishna!

Congratulations, Manjeet!

• Kumar M, I Ivanova M, Ramamoorthy A. Ganglioside GM1 produces stable, short, and cytotoxic Aβ40 protofibrils. Chem Commun (Camb). 2023 Jun 6;59(46):7040-7043.

*Welcoming Lina-Cerine Mechakra, Visiting Master's Student, CY Cergy Paris Universite, France

Congratulations Mary Muter for the summer fellowship award!

Congratulations Zhizhuo Zhang for the summer fellowship award!

*Welcoming Volodymyr Hiiuk, Research Fellow! 

*Welcoming Dr. Malitha C Dickwella Widanage, a post-doctoral fellow! 

Congratulations, Sam!

Magnetically aligned nanodiscs enable direct measurement of 17O residual quadrupolar coupling for small molecules. McCalpin SD, Fu R, Ravula T, Wu G, Ramamoorthy A.

J Magn Reson. 2023 Jan;346:107341. doi: 10.1016/j.jmr.2022.107341.

Congratulations Team for this wonderful product resulting from QFR (Quarantine From Reality) period!

Ultrafast Magic Angle Spinning Solid-State NMR Spectroscopy: Advances in Methodology and Applications. Nishiyama Y, Hou G, Agarwal V, Su Y, Ramamoorthy A.

Chem Rev. 2022 Dec 21. doi: 10.1021/acs.chemrev.2c00197.

Congratulations, Krishna!

Enhancing the stability and homogeneity of non-ionic polymer nanodiscs by tuning electrostatic interactions. Krishnarjuna B, Marte J, Ravula T, Ramamoorthy A.

J Colloid Interface Sci. 2022 Dec 21;634:887-896. doi: 10.1016/j.jcis.2022.12.112.

Congratulations, Sam, Bikash, and Argo!

Free Gangliosides Can Alter Amyloid-β Aggregation.

Chakravorty A, McCalpin SD, Sahoo BR, Ramamoorthy A, Brooks CL 3rd.

J Phys Chem Lett. 2022 Sep 29:9303-9308. 

*Welcoming Dr. Gaurav Sharma, a post-doctoral fellow! 

*Welcoming NamHoon Kim, undergraduate researcher! 

*Welcoming Bishvanwesha Panda, a graduate student from Chemistry!

Congratulations, Krishna, Thiru, and Joseph!

"Non-ionic inulin-based polymer-nanodiscs enable functional reconstitution of a redox complex composed of oppositely charged CYP450 and CPR in a lipid bilayer membrane"

Author(s): Krishnarjuna, Bankala; Im, Sang-Choul; Ravula, Thirupathi; Marte, Joseph; Auchus, Richard; Ramamoorthy, Ayyalusamy,  Analytical Chemistry 94,11908-11915.

Congratulations, Krishna!

"Detergent-Free Isolation of Membrane Proteins and Strategies to Study Them in a Near-Native Membrane Environment", Krishnarjuna B and Ramamoorthy A, Biomolecules; 12, 1076 (2022).

Welcoming a post-doctoral fellow, Dr. Manjeet Kumar, to the lab. 

Welcoming an undergraduate student, Mary Muter, to the lab. 

Congratulations, Krishna and Thiru!

"Detergent-free isolation of CYP450-reductase’s FMN-binding domain in E.coli lipid-nanodiscs using a charge-free polymer"

Bankala Krishnarjuna, Thirupathi Ravula, and Ayyalusamy Ramamoorthy, Chemical Communications 58, 4913-4916.

Sam publishes his first paper! 

Congratulations, Sam and Thiru!

"Saponins Form Nonionic Lipid Nanodiscs for Protein Structural

Studies by Nuclear Magnetic Resonance Spectroscopy"

Samuel D. McCalpin, Thirupathi Ravula, and Ayyalusamy Ramamoorthy, 

J. Phys. Chem. Letters (in press, 2022)

Srikar's NMR-Music study is published! Congratulations, Srikar!

This is an educational project. 

Munukutla S, Bertoy A, Rush S, Ramamoorthy A. "Molecular Music: A Modern Accompaniment to NMR Pedagogy." Journal of Chemical Education (2022). 

Thiru's "aligned & 90°-flipped nanodiscs" is published! Congratulations, Thiru!

Ravula T, Ramamoorthy A. "Measurement of Residual Dipolar Couplings Using Magnetically Aligned and Flipped Nanodiscs." Langmuir 38(1):244-252 (2022).

Bikash's IAPP study is published! Congratulations, Bikash!

Sahoo BR, Souders CL 2nd, Watanabe-Nakayama T, Deng Z, Linton H, Suladze S, Ivanova MI, Reif B, Ando T, Martyniuk CJ, Ramamoorthy A. "Conformational Tuning of Amylin by Charged Styrene-Maleic-Acid Copolymers." J Mol Biol. 434(2):167385 (2022).

Welcoming a post-doctoral fellow Dr. Mohammad Hajipour!

• Congratulation Thiru on his new job! Thiru joins the NMRFAM at the University of Wisconsin. 

• Thiru's manuscript accepted for publication - Congratulations, Thiru!

"Synthesis, Characterization, and Nanodisc formation of Non-ionic Polymers", Angew.Chem. (2021).

"A Solid-State NMR Study to Probe the Effects of Divalent Metal Ions (Ca2+ and Mg2+) on the Magnetic-Alignment of Polymer Based Lipid‐Nanodiscs", Langmuir (2021). 

Krishna's manuscripts accepted for publication - Congratulations, Krishna!

• "Nanodisc reconstitution of flavin mononucleotide binding domain of cytochrome-P450-reductase enables high-resolution NMR probing", Chemical Communications (2021).

• "Solid-state packing dictates the unexpected solubility of aromatic peptides", Cell Reports Physical Science (2021). 

•   see GenScript links on Krishna's publication on the direct 'detergent-free' extraction of cyt-b5: 

https://www.molecularcloud.org/p/winners-announced-of-membrane-protein-extraction-campaign

https://www.molecularcloud.org/p/molecularcloud-january-newsletter-detergent-free-extraction-of-membrane-protein#comment 

Congratulations, Bikash!

• "Degradation of Alzheimer’s amyloid-β by a catalytically inactive insulin-degrading enzyme", Journal of Molecular Biology (2021).

• "Investigation of the effects of two major secretory granules components, insulin and zinc, on human-IAPP amyloid aggregation and membrane damage", Chemistry and Physics of Lipids (2021).

• Bikash joined the HHMI institute as a staff scientist to work in the lab of Professor James Bardwell at Michigan. 

Congratulations, Katya (Katerina Kornievskaia) on your being awarded the summer undergraduate research fellowship from the Chemistry Department!

Congratulations, Dr. Giacomo Di Mauro!

• Giacomo's manuscript is now accepted for publication in Langmuir (Feb.2021).

• Giacomo successfully defends thesis research and graduates with a PhD degree in Chemistry (Dec.2020). 

• Giacomo is joining Professor Matthias Buck's research group in the Physiology and Biophysics Department at Case Western Reserve University, Cleveland (https://physiology.case.edu/research/labs/buck-lab/). (Jan.2021) 

 Congratulations to the Rams-lab Alumni

• Dr. Mohammad Hajipour accepts a Research Scientist position at Stanford University. 

• Dr. Thirupathi Ravula joins NMRFAM, University of Wisconsin - Madison. 

• Dr. Rui Huang becomes an Assistant Professor of Chemistry position at the University of Guelph, Canada. 

• Dr. Vojc Kocman accepted a faculty position at the Slovenian NMR Centre, Slovenia.

• Dr. Joshua Damron becomes a Scientist at the Oakridge National Lab, Tennessee, USA.

• Dr. Jeffrey Brender becomes a Staff Scientist at NCI, NIH.

• Dr. Nathaniel Hardin accepts a position at Savannah River National Lab, South Carolina USA. 

NMR and Music: Rams lab presents "NMR and Music." Please, check out our initiative here. Please, check out our initiative here.

Congratulations Nate for the post-doctoral fellow position in the Professor Bart's lab. Now (Jan.2021), joining the Savannah River National Lab! Best wishes.

Congratulations Sarah for the post-doctoral fellow position at the National University of Singapore! Best wishes.